Sector

Healthcare ETFs

Broad healthcare funds are defensive and pharma-heavy. Biotech sub-sector funds are the opposite: high beta, binary catalysts, and far less profitable underlying companies.

Sort6 funds

XLV

Health Care Select Sector SPDR

SPDR

S&P 500 healthcare. Defensive, pharma and managed-care weighted.

Fee: 0.08%
AUM: $36.4B
Yield: 1.6%

1Y: +11.2%
5Y ann.: +9.1%
10Y ann.: —
All-time: —

VHT

Vanguard Health Care ETF

Vanguard

All-cap US healthcare including small-cap biotech, at a Vanguard fee.

Fee: 0.09%
AUM: $17.1B
Yield: 1.4%

1Y: +10.4%
5Y ann.: +8.9%
10Y ann.: —
All-time: —

IBB

iShares Biotechnology ETF

iShares

Large-cap biotech. Higher volatility, no pharma or device diversification.

Fee: 0.45%
AUM: $6.8B
Yield: 0.2%

1Y: +14.6%
5Y ann.: +2.4%
10Y ann.: —
All-time: —

XBI

SPDR S&P Biotech ETF

SPDR

Equal-weighted biotech dominated by small-cap clinical-stage names. Very high beta.

Fee: 0.35%
AUM: $6.2B
Yield: 0.0%

1Y: +19.4%
5Y ann.: -3.6%
10Y ann.: —
All-time: —

IHI

iShares U.S. Medical Devices ETF

iShares

Medical devices only — procedure-volume exposure without drug-pricing risk.

Fee: 0.40%
AUM: $4.8B
Yield: 0.6%

1Y: +6.8%
5Y ann.: +5.2%
10Y ann.: —
All-time: —

PPH

VanEck Pharmaceutical ETF

VanEck

Global large-cap pharma only, including European names like Novo and Roche.

Fee: 0.36%
AUM: $700M
Yield: 2.4%

1Y: +13.1%
5Y ann.: +9.8%
10Y ann.: —
All-time: —